|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:amendedBy
|
phosphorylation
methylation
acetylation
|
|
gptkbp:binds
|
exonic splicing enhancers
|
|
gptkbp:discoveredBy
|
Xiang-Dong Fu
|
|
gptkbp:discoveredIn
|
1992
|
|
gptkbp:example
|
gptkb:SRSF2
gptkb:SRSF1
gptkb:SRSF10
gptkb:SRSF11
gptkb:SRSF12
gptkb:SRSF3
gptkb:SRSF6
gptkb:SRSF7
gptkb:SRSF9
SRSF4
SRSF5
|
|
gptkbp:feature
|
contain RNA recognition motif
contain RS domain
|
|
gptkbp:foundIn
|
eukaryotes
|
|
gptkbp:fullName
|
Serine/arginine-rich proteins
|
|
gptkbp:function
|
splicing regulation
alternative splicing
mRNA export
|
|
gptkbp:interactsWith
|
gptkb:RNA_polymerase_II
U1 snRNP
U2AF
|
|
gptkbp:involvedIn
|
gene expression regulation
RNA metabolism
spliceosome assembly
|
|
gptkbp:involves
|
gptkb:cancer
neurodegenerative diseases
splicing diseases
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:phosphorylates
|
SR protein kinases
|
|
gptkbp:proteinFamily
|
9G8 family
SC35 family
SRRM family
SRSF family
SRp20 family
SRp40 family
SRp55 family
SRp75 family
TRA2 family
|
|
gptkbp:recognizedBy
|
antibodies
|
|
gptkbp:bfsParent
|
gptkb:CLK_(CDK-like_kinase)
gptkb:Ewing_sarcoma_breakpoint_region_1
gptkb:Hnrnpa1
gptkb:SRSF_proteins
gptkb:U2AF65
gptkb:heterogeneous_nuclear_ribonucleoprotein_A1
gptkb:heterogeneous_nuclear_ribonucleoproteins_(hnRNPs)
gptkb:transformer_(Isotype)
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SR proteins
|