Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:amendedBy |
phosphorylation
methylation acetylation |
| gptkbp:binds |
exonic splicing enhancers
|
| gptkbp:discoveredBy |
Xiang-Dong Fu
|
| gptkbp:discoveredIn |
1992
|
| gptkbp:example |
gptkb:SRSF2
gptkb:SRSF1 gptkb:SRSF10 gptkb:SRSF11 gptkb:SRSF12 gptkb:SRSF3 gptkb:SRSF6 gptkb:SRSF7 gptkb:SRSF9 SRSF4 SRSF5 |
| gptkbp:feature |
contain RNA recognition motif
contain RS domain |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:fullName |
Serine/arginine-rich proteins
|
| gptkbp:function |
splicing regulation
alternative splicing mRNA export |
| https://www.w3.org/2000/01/rdf-schema#label |
SR proteins
|
| gptkbp:interactsWith |
gptkb:RNA_polymerase_II
U1 snRNP U2AF |
| gptkbp:involvedIn |
gene expression regulation
RNA metabolism spliceosome assembly |
| gptkbp:involves |
gptkb:cancer
neurodegenerative diseases splicing diseases |
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:phosphorylates |
SR protein kinases
|
| gptkbp:proteinFamily |
9G8 family
SC35 family SRRM family SRSF family SRp20 family SRp40 family SRp55 family SRp75 family TRA2 family |
| gptkbp:recognizedBy |
antibodies
|
| gptkbp:bfsParent |
gptkb:transformer_(Isotype)
|
| gptkbp:bfsLayer |
7
|