EWS RNA-binding protein 1

URI: https://gptkb.org/entity/EWS_RNA-binding_protein_1

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:EWS EWSR1 protein Ewing sarcoma breakpoint region 1 protein
gptkbp:associatedWith	gptkb:Ewing_sarcoma gptkb:myxoid_liposarcoma gptkb:desmoplastic_small_round_cell_tumor
gptkbp:biologicalProcess	cell proliferation DNA repair mRNA processing transcription elongation
gptkbp:discoveredBy	1992
gptkbp:domain	RNA recognition motif glycine-rich domain prion-like domain
gptkbp:Entrez_Gene_ID	2130 ENSG00000012048
gptkbp:formsFusionGeneWith	gptkb:WT1 gptkb:ATF1 gptkb:DDIT3 gptkb:ERG gptkb:FLI1
gptkbp:function	RNA binding splicing regulation transcription regulation
gptkbp:gene	gptkb:EWSR1
gptkbp:HGNC_ID	3508
https://www.w3.org/2000/01/rdf-schema#label	EWS RNA-binding protein 1
gptkbp:interactsWith	gptkb:RNA_polymerase_II gptkb:FUS gptkb:CREB-binding_protein gptkb:TAF15 gptkb:hnRNPs YBX1
gptkbp:locatedOnChromosome	chromosome 22 22q12.2
gptkbp:location	gptkb:nucleus
gptkbp:molecularWeight	68 kDa
gptkbp:OMIM	133450
gptkbp:orthologInMouse	Ewsr1
gptkbp:postTranslationalModification	phosphorylation methylation
gptkbp:subcellularLocation	nucleoplasm nuclear speckles
gptkbp:UniProtID	Q01844
gptkbp:bfsParent	gptkb:EWSR1
gptkbp:bfsLayer	7