Enhancer of zeste 2 polycomb repressive complex 2 subunit
GPTKB entity
Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alias |
gptkb:EZH2
gptkb:ENX1 gptkb:KMT6 |
| gptkbp:amendedBy |
histone H3 lysine 27
|
| gptkbp:associatedWith |
gptkb:cancer
gene silencing |
| gptkbp:biologicalProcess |
transcriptional repressor activity
|
| gptkbp:component |
gptkb:Polycomb_repressive_complex_2
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000106462
|
| gptkbp:function |
histone methyltransferase activity
|
| gptkbp:gene |
gptkb:EZH2
|
| gptkbp:HGNC_ID |
3527
|
| https://www.w3.org/2000/01/rdf-schema#label |
Enhancer of zeste 2 polycomb repressive complex 2 subunit
|
| gptkbp:involves |
cell proliferation
stem cell maintenance epigenetic regulation |
| gptkbp:locatedIn |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
7q36.1
|
| gptkbp:OMIM |
601573
|
| gptkbp:orthologInMouse |
gptkb:Ezh2
|
| gptkbp:PDB |
gptkb:5HYN
|
| gptkbp:RefSeq |
NM_004456
|
| gptkbp:target |
small molecule inhibitors
|
| gptkbp:UniProtID |
gptkb:Q15910
|
| gptkbp:bfsParent |
gptkb:EZH2_(human)
|
| gptkbp:bfsLayer |
8
|