|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:BCC7
gptkb:LFS1
gptkb:TRP53
P53
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Li-Fraumeni_syndrome
colorectal cancer
adrenocortical carcinoma
osteosarcoma
|
|
gptkbp:biologicalProcess
|
DNA repair
regulation of transcription
apoptotic process
cell cycle arrest
protein binding
DNA binding
transcription factor activity
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:describes
|
gptkb:tumor_protein_p53
|
|
gptkbp:discoveredBy
|
gptkb:Arnold_Levine
gptkb:Lloyd_Old
gptkb:David_Lane
|
|
gptkbp:discoveredIn
|
1979
|
|
gptkbp:Entrez_Gene_ID
|
7157
|
|
gptkbp:function
|
gptkb:transcription_factor
gptkb:tumor_suppressor
|
|
gptkbp:gene
|
gptkb:TP53
|
|
gptkbp:geneType
|
protein_coding
|
|
gptkbp:hasTranscript
|
gptkb:ENST00000269305
ENST00000413465
ENST00000420246
ENST00000445888
|
|
gptkbp:HGNC_ID
|
HGNC:11998
|
|
gptkbp:length
|
20475
|
|
gptkbp:locatedOnChromosome
|
17
17p13.1
|
|
gptkbp:OMIM
|
191170
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Trp53
gptkb:zebrafish_tp53
|
|
gptkbp:pathway
|
apoptosis
cell cycle
DNA damage response
p53 signaling pathway
|
|
gptkbp:strand
|
negative
|
|
gptkbp:UniProtID
|
P04637
|
|
gptkbp:bfsParent
|
gptkb:DLG1_(human)
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ENSG00000141493
|