|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:2-phospho-D-glycerate_hydro-lyase
NNE
ENOA
MPB-1
|
|
gptkbp:alternativeName
|
gptkb:phosphopyruvate_hydratase
MBP-1
non-neuronal enolase
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
autoimmune diseases
|
|
gptkbp:clinicalMarker
|
biomarker
autoantigen in Hashimoto's encephalopathy
|
|
gptkbp:cofactor
|
magnesium ion
|
|
gptkbp:discoveredBy
|
1960s
|
|
gptkbp:Entrez_Gene_ID
|
2023
ENSG00000074800
|
|
gptkbp:enzymeCommissionNumber
|
4.2.1.11
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
brain
liver
many tissues
|
|
gptkbp:fullName
|
Alpha-enolase
|
|
gptkbp:function
|
glycolytic enzyme
catalyzes conversion of 2-phosphoglycerate to phosphoenolpyruvate
|
|
gptkbp:gene
|
gptkb:ENO1
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
3349
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ENO1
|
|
gptkbp:inhibitedBy
|
gptkb:fluoride
phosphonoacetohydroxamate
|
|
gptkbp:interactsWith
|
gptkb:PLG
gptkb:MYC
gptkb:HSPA8
|
|
gptkbp:length
|
434 amino acids
|
|
gptkbp:locatedOnChromosome
|
1
|
|
gptkbp:location
|
gptkb:1p36.23
|
|
gptkbp:molecularWeight
|
47 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Eno1
|
|
gptkbp:orthologInYeast
|
gptkb:ENO1
|
|
gptkbp:pathway
|
glycolysis
gluconeogenesis
|
|
gptkbp:PDB
|
2PSN
3B97
4ZCW
|
|
gptkbp:postTranslationalModification
|
phosphorylation
methylation
acetylation
|
|
gptkbp:proteinFamily
|
enolase family
|
|
gptkbp:regulates
|
MYC transcription
|
|
gptkbp:reviewedBy
|
gptkb:GeneCards
gptkb:NCBI_Gene
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:subcellularLocation
|
gptkb:cell_membrane
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P06733
|
|
gptkbp:bfsParent
|
gptkb:Enolase
gptkb:enolase
|
|
gptkbp:bfsLayer
|
7
|