|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:2-phospho-D-glycerate_hydro-lyase
gptkb:phosphopyruvate_hydratase
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:glioblastoma
muscular dystrophy
|
|
gptkbp:cofactor
|
magnesium
|
|
gptkbp:discoveredBy
|
1934
|
|
gptkbp:EC_number
|
4.2.1.11
|
|
gptkbp:foundIn
|
gptkb:cell_membrane
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:function
|
catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate
|
|
gptkbp:gene
|
gptkb:ENO2
gptkb:ENO1
gptkb:ENO3
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Enolase
|
|
gptkbp:inhibitedBy
|
gptkb:fluoride
|
|
gptkbp:interactsWith
|
gptkb:actin
gptkb:plasminogen
tubulin
|
|
gptkbp:locale
|
multifunctional protein
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_12_(ENO2)
gptkb:chromosome_17_(ENO3)
gptkb:chromosome_1_(ENO1)
|
|
gptkbp:molecularWeight
|
~47 kDa
|
|
gptkbp:pathway
|
glycolysis
|
|
gptkbp:PDB
|
1EBH
|
|
gptkbp:postTranslationalModification
|
phosphorylation
methylation
acetylation
|
|
gptkbp:presentIn
|
gptkb:Bacteria
animals
fungi
plants
|
|
gptkbp:role
|
autoantigen in autoimmune diseases
moonlighting protein
|
|
gptkbp:significance
|
marker for neuronal damage
marker for certain cancers
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:subunit
|
gptkb:alpha-enolase
gptkb:beta-enolase
gptkb:gamma-enolase
|
|
gptkbp:UniProtID
|
gptkb:P06733
|
|
gptkbp:used_as_marker
|
stroke
Small Cell Lung Cancer
neuroendocrine tumors
|
|
gptkbp:bfsParent
|
gptkb:Enzymes
|
|
gptkbp:bfsLayer
|
6
|