Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:E6-associated_protein
UBE3A protein |
| gptkbp:associatedWith |
gptkb:autism_spectrum_disorder
gptkb:Angelman_syndrome |
| gptkbp:encodedBy |
gptkb:UBE3A_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
gptkb:E3_ubiquitin-protein_ligase
|
| https://www.w3.org/2000/01/rdf-schema#label |
E6AP protein
|
| gptkbp:interactsWith |
gptkb:p53_protein
gptkb:HPV_E6_protein |
| gptkbp:involvedIn |
gptkb:ubiquitin-proteasome_pathway
|
| gptkbp:locatedOnChromosome |
gptkb:15q11-q13
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
~100 kDa
|
| gptkbp:mutationAssociatedWith |
causes Angelman syndrome
linked to neurodevelopmental disorders |
| gptkbp:postTranslationalModification |
phosphorylation
ubiquitination |
| gptkbp:UniProtID |
gptkb:Q05086
|
| gptkbp:bfsParent |
gptkb:E6AP-type_E3_ubiquitin_ligase_domain
|
| gptkbp:bfsLayer |
8
|