Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:binds |
E2F DNA binding site
|
| gptkbp:discoveredBy |
1980s
|
| gptkbp:expressedIn |
eukaryotic cells
|
| gptkbp:function |
transcription factor
|
| gptkbp:gene |
gptkb:E2F
|
| gptkbp:hasMember |
gptkb:E2F2
gptkb:E2F3 gptkb:E2F4 gptkb:E2F5 gptkb:E2F6 gptkb:E2F7 gptkb:E2F8 gptkb:E2F1 |
| https://www.w3.org/2000/01/rdf-schema#label |
E2F proteins
|
| gptkbp:interactsWith |
gptkb:retinoblastoma_protein
|
| gptkbp:involves |
tumor suppression
cancer development |
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:modulatedBy |
gptkb:cyclin-dependent_kinases
p53 pathway CDK inhibitors Rb pathway |
| gptkbp:regulates |
apoptosis
cell proliferation cell cycle DNA synthesis |
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens gptkb:Drosophila_melanogaster |
| gptkbp:bfsParent |
gptkb:DP_proteins
|
| gptkbp:bfsLayer |
8
|