Statements (60)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Dopamine receptor
|
| gptkbp:associatedWith |
gptkb:schizophrenia
Parkinson's disease |
| gptkbp:barrelLength |
dopamine
|
| gptkbp:communitySupport |
sleep
sexual behavior appetite motor control reward pathways |
| gptkbp:hasRole |
mood disorders
cognitive disorders psychotic disorders behavioral disorders |
| gptkbp:hasVariants |
SNPs
genetic polymorphisms |
| https://www.w3.org/2000/01/rdf-schema#label |
Dopamine receptor D2
|
| gptkbp:influences |
decision making
mood cognition social behavior risk-taking behavior dopaminergic signaling |
| gptkbp:interactsWith |
G-proteins
|
| gptkbp:involvedIn |
emotional regulation
addiction learning memory stress response neurotransmission impulse control alcohol dependence cocaine dependence drug dependence endocrine regulation nicotine dependence opioid dependence reward learning |
| gptkbp:is_evaluated_by |
neurons
|
| gptkbp:isActiveIn |
gptkb:adenylate_cyclase
cAMP production |
| gptkbp:isInvolvedIn |
gptkb:Tourette_syndrome
neurodegenerative diseases chronic pain sleep disorders anxiety disorders bipolar disorder ADHD eating disorders mood disorders obsessive-compulsive disorder autism spectrum disorders |
| gptkbp:isTrainedIn |
gptkb:dopamine_agonists
dopamine antagonists |
| gptkbp:locatedIn |
brain
substantia nigra ventral tegmental area striatum |
| gptkbp:subclass |
D2L
D2S |
| gptkbp:targets |
antipsychotic drugs
|