|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CYPA
gptkb:PPIA
gptkb:peptidylprolyl_isomerase_A
|
|
gptkbp:associatedWith
|
gptkb:cancer
cardiovascular diseases
inflammatory diseases
|
|
gptkbp:binds
|
cyclosporin A
|
|
gptkbp:discoveredBy
|
gptkb:Takashi_Uchida
|
|
gptkbp:discoveredIn
|
1984
|
|
gptkbp:encodedBy
|
gptkb:PPIA_gene
|
|
gptkbp:Entrez_Gene_ID
|
5478
|
|
gptkbp:enzymeCommissionNumber
|
EC 5.2.1.8
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
protein folding
peptidyl-prolyl cis-trans isomerase activity
|
|
gptkbp:GO_term
|
GO:0003755
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cyclophilin A
|
|
gptkbp:inhibitedBy
|
cyclosporin A
|
|
gptkbp:interactsWith
|
gptkb:HIV-1_capsid_protein
|
|
gptkbp:involvedIn
|
immunosuppression
|
|
gptkbp:locatedOnChromosome
|
chromosome 7p13
|
|
gptkbp:molecularWeight
|
18 kDa
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:partOf
|
gptkb:cyclophilin_protein_family
|
|
gptkbp:PDB
|
gptkb:1AK4
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
|
gptkbp:role
|
HIV-1 infectivity
|
|
gptkbp:sequence
|
165 amino acids
|
|
gptkbp:structure
|
single polypeptide chain
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
P62937
|
|
gptkbp:bfsParent
|
gptkb:CYPA
|
|
gptkbp:bfsLayer
|
7
|