|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:Cyclophilin_A
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:cardiovascular_disease
inflammatory diseases
rheumatoid arthritis
HIV-1 infection
|
|
gptkbp:biologicalProcess
|
peptidyl-prolyl cis-trans isomerase activity
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:conservedIn
|
mammals
|
|
gptkbp:discoveredBy
|
gptkb:Takashi_Uchida
|
|
gptkbp:discoveredIn
|
1984
|
|
gptkbp:encodes
|
gptkb:peptidylprolyl_isomerase_A
|
|
gptkbp:Entrez_Gene_ID
|
5478
ENSG00000196262
|
|
gptkbp:expressedIn
|
gptkb:human
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
immunosuppression
protein folding
|
|
gptkbp:gene
|
gptkb:PPIA
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOID
|
GO:0005737
GO:0005524
GO:0003755
GO:0005654
|
|
gptkbp:hasTranscriptVariant
|
NM_021130
|
|
gptkbp:HGNC_ID
|
HGNC:9253
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PPIA
|
|
gptkbp:inhibitedBy
|
cyclosporin A
|
|
gptkbp:interactsWith
|
cyclosporin A
|
|
gptkbp:involvedIn
|
protein folding
immune response
|
|
gptkbp:length
|
165 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7
|
|
gptkbp:molecularWeight
|
18 kDa
|
|
gptkbp:OMIM
|
123840
|
|
gptkbp:orthologInMouse
|
gptkb:Ppia
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
|
gptkbp:proteinFamily
|
gptkb:cyclophilin
gptkb:cyclophilin-type_PPIase_domain
|
|
gptkbp:regulates
|
T-cell activation
|
|
gptkbp:structure
|
single exon gene
|
|
gptkbp:subcellularLocation
|
cytosol
extracellular space
|
|
gptkbp:tissue_specificity
|
ubiquitous
|
|
gptkbp:UniProtID
|
P62937
|
|
gptkbp:bfsParent
|
gptkb:CYPA
|
|
gptkbp:bfsLayer
|
7
|