Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
p24
CA protein |
| gptkbp:encodedBy |
HIV-1 gag gene
|
| gptkbp:foundIn |
gptkb:HIV-1
|
| gptkbp:function |
forms the conical core of HIV-1 virion
mediates uncoating during infection protects viral RNA genome |
| https://www.w3.org/2000/01/rdf-schema#label |
HIV-1 capsid protein
|
| gptkbp:interactsWith |
TRIM5alpha
host cyclophilin A |
| gptkbp:length |
231 amino acids
|
| gptkbp:molecularWeight |
~24 kDa
|
| gptkbp:PDB |
3H47
|
| gptkbp:postTranslationalModification |
phosphorylation
ubiquitination |
| gptkbp:recognizedBy |
anti-p24 antibodies
|
| gptkbp:roleInLifeCycle |
viral assembly
viral maturation early post-entry events |
| gptkbp:structure |
composed of N-terminal and C-terminal domains
forms hexamers and pentamers |
| gptkbp:target |
antiretroviral drugs
host immune response |
| gptkbp:taxonRank |
gptkb:Human_immunodeficiency_virus_type_1
|
| gptkbp:UniProtID |
P12497
|
| gptkbp:usedIn |
HIV diagnostic assays
|
| gptkbp:bfsParent |
gptkb:p24_antigen
|
| gptkbp:bfsLayer |
7
|