Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
PIK3C2
|
| gptkbp:catalyzes |
phosphorylation of phosphatidylinositol 4-phosphate
phosphorylation of phosphatidylinositol |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:domain |
C2 domain
PI3K catalytic domain PI3K helical domain |
| gptkbp:enzymeClassification |
gptkb:EC_2.7.1.153
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:hasIsoform |
gptkb:PIK3C2A
gptkb:PIK3C2B gptkb:PIK3C2G |
| https://www.w3.org/2000/01/rdf-schema#label |
Class IV PI3K
|
| gptkbp:involvedIn |
cell survival
cell growth cell signaling endocytosis membrane trafficking |
| gptkbp:produces |
gptkb:phosphatidylinositol_3,4-bisphosphate
phosphatidylinositol 3-phosphate |
| gptkbp:regulates |
gptkb:insulin
gptkb:receptor_tyrosine_kinases growth factors |
| gptkbp:relatedTo |
gptkb:Class_III_PI3K
gptkb:Class_II_PI3K gptkb:Class_I_PI3K |
| gptkbp:bfsParent |
gptkb:phosphoinositide_3-kinase_family
|
| gptkbp:bfsLayer |
6
|