Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:Vps34
|
| gptkbp:catalyzes |
phosphorylation of phosphatidylinositol to phosphatidylinositol 3-phosphate
|
| gptkbp:discoveredIn |
gptkb:yeast
|
| gptkbp:familyMember |
phosphoinositide 3-kinases
|
| gptkbp:formsComplexWith |
gptkb:Beclin-1
gptkb:p150_(Vps15) |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:gene |
gptkb:PIK3C3
|
| https://www.w3.org/2000/01/rdf-schema#label |
Class III PI3K
|
| gptkbp:involvedIn |
autophagy
endocytic trafficking |
| gptkbp:regulates |
autophagosome formation
lysosomal function vesicle-mediated transport |
| gptkbp:requires |
autophagosome nucleation
|
| gptkbp:subunit |
gptkb:catalytic_subunit_Vps34
gptkb:regulatory_subunit_Vps15 |
| gptkbp:target |
gptkb:3-methyladenine
gptkb:Wortmannin autophagy inhibitors |
| gptkbp:bfsParent |
gptkb:protein
|
| gptkbp:bfsLayer |
4
|