Cell division protein kinase 2

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	gptkb:CDK2
gptkbp:associatedWith	gptkb:cancer
gptkbp:biologicalProcess	DNA replication G1/S transition of mitotic cell cycle
gptkbp:discoveredBy	1990s
gptkbp:EC_number	2.7.11.22
gptkbp:enzymeClassification	serine/threonine-protein kinase
gptkbp:form	complexed with cyclins
gptkbp:function	regulation of cell cycle
gptkbp:gene	gptkb:CDK2
gptkbp:inhibitedBy	gptkb:roscovitine gptkb:p21Cip1 gptkb:p27Kip1
gptkbp:locatedOnChromosome	chromosome 12q13
gptkbp:location	gptkb:nucleus gptkb:cytoplasm
gptkbp:molecularWeight	33 kDa
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:orthologIn	gptkb:mouse_Cdk2 gptkb:rat_Cdk2
gptkbp:PDB	1FIN
gptkbp:postTranslationalModification	phosphorylation
gptkbp:requires	cell proliferation
gptkbp:structure	gptkb:monomer forms heterodimer with cyclin E or cyclin A
gptkbp:substrate	gptkb:Rb_protein gptkb:p27Kip1
gptkbp:UniProtID	P24941
gptkbp:bfsParent	gptkb:P34130
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	Cell division protein kinase 2