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gptkbp:instanceOf
|
gptkb:protein
gptkb:CRISPR-Cas_system
|
|
gptkbp:alternativeName
|
gptkb:Cpf1
|
|
gptkbp:cleavage
|
single-stranded DNA
double-stranded DNA
staggered ends
|
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gptkbp:compatibleWith
|
gptkb:tracrRNA
|
|
gptkbp:component
|
adaptive immune system in prokaryotes
|
|
gptkbp:discoveredIn
|
2015
|
|
gptkbp:foundIn
|
gptkb:Bacteria
archaea
|
|
gptkbp:function
|
gptkb:DNA_endonuclease
genome editing
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cas12 protein
|
|
gptkbp:mechanismOfAction
|
RNA-guided
|
|
gptkbp:recognizedBy
|
PAM sequence
|
|
gptkbp:relatedTo
|
gptkb:Cas9_protein
|
|
gptkbp:requires
|
gptkb:crRNA
|
|
gptkbp:sequenceSpecificity
|
high
|
|
gptkbp:studiedBy
|
gptkb:Feng_Zhang
gptkb:Jennifer_Doudna
|
|
gptkbp:subspecies
|
gptkb:Cas12a
gptkb:Cas12b
gptkb:Cas12c
gptkb:Cas12d
gptkb:Cas12e
gptkb:Cas12f
|
|
gptkbp:usedFor
|
diagnostics
gene editing
gene knockout
|
|
gptkbp:usedIn
|
gptkb:DETECTR_diagnostic_platform
gptkb:SHERLOCK_diagnostic_platform
gptkb:CRISPR-Cas12_system
|
|
gptkbp:bfsParent
|
gptkb:CRISPR-Cas12_genome_editing_technology
|
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gptkbp:bfsLayer
|
5
|