|
gptkbp:instanceOf
|
gptkb:protein
cytokine
|
|
gptkbp:alternativeName
|
IP-10
Interferon gamma-induced protein 10
Small-inducible cytokine B10
|
|
gptkbp:component
|
extracellular space
|
|
gptkbp:discoveredIn
|
1985
|
|
gptkbp:encodedBy
|
CXCL10 gene
|
|
gptkbp:Entrez_Gene_ID
|
3627
ENSG00000169245
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
gptkb:keratinocytes
endothelial cells
fibroblasts
|
|
gptkbp:family
|
CXC chemokine family
|
|
gptkbp:foundIn
|
blood plasma
tissues during inflammation
|
|
gptkbp:function
|
chemokine activity
chemoattractant for NK cells
chemoattractant for T cells
chemoattractant for dendritic cells
chemoattractant for monocytes
|
|
gptkbp:GOProcess
|
immune system process
chemotaxis
|
|
gptkbp:HGNC_ID
|
10637
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CXCL10
|
|
gptkbp:inducedBy
|
gptkb:interferon-gamma
|
|
gptkbp:involvedIn
|
immune response
inflammatory response
|
|
gptkbp:length
|
98 amino acids
|
|
gptkbp:locatedOnChromosome
|
4q21.1
|
|
gptkbp:molecularWeight
|
8.7 kDa
|
|
gptkbp:OMIM
|
147310
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
1LV9
|
|
gptkbp:postTranslationalModification
|
glycosylation
proteolytic processing
|
|
gptkbp:recipient
|
gptkb:CXCR3
|
|
gptkbp:RefSeq
|
NM_001565
|
|
gptkbp:relatedTo
|
gptkb:CXCL11
gptkb:CXCL4
gptkb:CXCL9
|
|
gptkbp:role
|
gptkb:cancer
infectious diseases
autoimmune diseases
inflammatory diseases
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
contains four conserved cysteine residues
|
|
gptkbp:UniProtID
|
P02778
|
|
gptkbp:bfsParent
|
gptkb:CXCR3
gptkb:CXC_domain
|
|
gptkbp:bfsLayer
|
8
|