cyclin-dependent kinase inhibitor 1C

URI: https://gptkb.org/entity/cyclin-dependent_kinase_inhibitor_1C
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alternativeName gptkb:CDKN1C
gptkb:p57Kip2
gptkbp:biologicalProcess cell differentiation
negative regulation of cell proliferation
protein binding
kinase inhibitor activity
gptkbp:encodedBy gptkb:CDKN1C_gene
gptkbp:Entrez_Gene_ID gptkb:ENSG00000129757
gptkb:CDKN1C
1028
gptkbp:expressedIn various tissues
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function cell cycle regulation
cyclin-dependent kinase inhibitor
gptkbp:HGNC_ID 1786
https://www.w3.org/2000/01/rdf-schema#label cyclin-dependent kinase inhibitor 1C
gptkbp:inhibitedBy cyclin/CDK complexes
gptkbp:isImprinted true
gptkbp:length 316 amino acids
gptkbp:locatedOnChromosome gptkb:11p15.5
gptkbp:molecularWeight 32 kDa
gptkbp:mutationAssociatedWith gptkb:IMAGe_syndrome
gptkb:Beckwith-Wiedemann_syndrome
gptkb:Silver-Russell_syndrome
gptkbp:OMIM 600856
gptkbp:parentalExpression maternal allele
gptkbp:regulates G1 phase of cell cycle
gptkbp:subcellularLocation gptkb:nucleus
gptkbp:UniProtID gptkb:P49918
gptkbp:bfsParent gptkb:CDKN1C
gptkbp:bfsLayer 6