|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:alias
|
gptkb:TAK
CDC2L4
PITALRE
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
HIV infection
|
|
gptkbp:biologicalProcess
|
cell cycle regulation
protein serine/threonine kinase activity
transcription elongation
HIV-1 transcription
|
|
gptkbp:component
|
P-TEFb complex
|
|
gptkbp:encodedBy
|
CDK9 gene
|
|
gptkbp:Entrez_Gene_ID
|
1025
|
|
gptkbp:enzymeCommissionNumber
|
2.7.11.23
|
|
gptkbp:formsComplexWith
|
Cyclin T1
Cyclin K
Cyclin T2
|
|
gptkbp:fullName
|
Cyclin-dependent kinase 9
|
|
gptkbp:function
|
regulation of transcription
phosphorylation of RNA polymerase II
|
|
gptkbp:gene
|
gptkb:CDK9
|
|
gptkbp:HGNC_ID
|
HGNC:1772
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CDK9
|
|
gptkbp:inhibitedBy
|
gptkb:flavopiridol
dinaciclib
SNS-032
|
|
gptkbp:interactsWith
|
gptkb:AFF4
BRD4
HEXIM1
Tat protein (HIV-1)
|
|
gptkbp:locatedOnChromosome
|
9q34.1
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Cdk9
rat Cdk9
|
|
gptkbp:pathway
|
cell cycle
HIV life cycle
transcriptional regulation by P-TEFb
|
|
gptkbp:phosphorylates
|
RNA polymerase II CTD
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
|
gptkbp:regulates
|
gene expression
|
|
gptkbp:requires
|
cell viability
transcriptional elongation
|
|
gptkbp:structure
|
protein kinase domain
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
P50750
|
|
gptkbp:bfsParent
|
gptkb:flavopiridol
gptkb:roscovitine
|
|
gptkbp:bfsLayer
|
6
|