CD82 gene

GPTKB entity

Statements (37)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alsoKnownAs gptkb:KAI1
R2
TSPAN27
gptkbp:associatedWith gptkb:cancer
prostate cancer
suppression of metastasis
gptkbp:biologicalProcess cell surface receptor
inhibits tumor metastasis
interacts with CD63
interacts with CD9
interacts with EGFR
interacts with integrins
modulates integrin signaling
gptkbp:discoveredIn 1995
gptkbp:downregulatedIn metastatic tumors
gptkbp:encodes CD82 protein
gptkbp:Entrez_Gene_ID 3732
ENSG00000177301
gptkbp:expressedIn various tissues
gptkbp:HGNC_ID HGNC:620
https://www.w3.org/2000/01/rdf-schema#label CD82 gene
gptkbp:length 8 exons
gptkbp:locatedOnChromosome chromosome 11
gptkbp:memberOf tetraspanin family
gptkbp:mutationAssociatedWith cancer progression
gptkbp:OMIM 600623
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse gptkb:Cd82
gptkbp:product CD82 antigen
gptkbp:regulates signal transduction
cell migration
cell adhesion
gptkbp:UniProtID P27701
gptkbp:upregulatedBy gptkb:p53
gptkbp:bfsParent gptkb:CD82
gptkbp:bfsLayer 8