ITAM (immunoreceptor tyrosine-based activation motif)
GPTKB entity
Statements (16)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
protein domain motif
|
| gptkbp:abbreviation |
immunoreceptor tyrosine-based activation motif
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:foundIn |
immunoreceptor cytoplasmic tails
|
| gptkbp:function |
signal transduction
|
| https://www.w3.org/2000/01/rdf-schema#label |
ITAM (immunoreceptor tyrosine-based activation motif)
|
| gptkbp:motif |
YxxL/Ix(6-8)YxxL/I
|
| gptkbp:phosphorylates |
gptkb:Src_family_kinases
|
| gptkbp:presentIn |
gptkb:T_cell_receptor_complex
gptkb:B_cell_receptor_complex Fc receptor |
| gptkbp:recognizedBy |
Syk family kinases
|
| gptkbp:role |
immune cell activation
|
| gptkbp:bfsParent |
gptkb:CD79a
gptkb:CD79b |
| gptkbp:bfsLayer |
7
|