Cluster of Differentiation 74
GPTKB entity
Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
cell surface receptor |
| gptkbp:alsoKnownAs |
gptkb:HLA_class_II_histocompatibility_antigen_gamma_chain
gptkb:CD74 |
| gptkbp:encodedBy |
gptkb:CD74_gene
|
| gptkbp:Entrez_Gene_ID |
972
|
| gptkbp:expressedIn |
gptkb:B_cells
dendritic cells macrophages monocytes |
| gptkbp:foundIn |
humans
mice |
| gptkbp:function |
involved in antigen presentation
regulates MHC class II molecules acts as a receptor for macrophage migration inhibitory factor (MIF) |
| https://www.w3.org/2000/01/rdf-schema#label |
Cluster of Differentiation 74
|
| gptkbp:involvedIn |
immune response
inflammatory response |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_5q32
|
| gptkbp:location |
gptkb:cell_membrane
endosomal compartments |
| gptkbp:significance |
implicated in cancer
implicated in autoimmune diseases |
| gptkbp:UniProtID |
gptkb:P04233
|
| gptkbp:bfsParent |
gptkb:CD74
|
| gptkbp:bfsLayer |
8
|