Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:PD-1
gptkb:Programmed_cell_death_protein_1 |
| gptkbp:discoveredIn |
1992
|
| gptkbp:domain |
ITIM motif
ITSM motif IgV-like domain |
| gptkbp:encodedBy |
gptkb:PDCD1_gene
|
| gptkbp:Entrez_Gene_ID |
5133
|
| gptkbp:expressedIn |
gptkb:B_cells
gptkb:T_cells myeloid cells |
| gptkbp:foundIn |
humans
mice |
| gptkbp:function |
immunotherapy
inhibits T cell activity |
| gptkbp:HGNC_ID |
gptkb:HGNC:8765
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD279
|
| gptkbp:ligand |
gptkb:PD-L2
PD-L1 |
| gptkbp:locatedOnChromosome |
gptkb:2q37.3_(human)
|
| gptkbp:OMIM |
600244
|
| gptkbp:role |
immunotherapy
autoimmune disease regulation |
| gptkbp:structure |
type I transmembrane protein
|
| gptkbp:target |
gptkb:pembrolizumab
gptkb:cemiplimab gptkb:nivolumab immunotherapy drugs |
| gptkbp:UniProtID |
Q15116
|
| gptkbp:bfsParent |
gptkb:programmed_cell_death_protein_1_(PD-1)
|
| gptkbp:bfsLayer |
6
|