|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:B7-H1
PD-L1
CD274 molecule
|
|
gptkbp:associatedWith
|
gptkb:cancer
autoimmune diseases
|
|
gptkbp:discoveredIn
|
1999
|
|
gptkbp:encodes
|
Programmed death-ligand 1
|
|
gptkbp:Entrez_Gene_ID
|
29126
ENSG00000120217
|
|
gptkbp:expressedIn
|
immune cells
tumor cells
|
|
gptkbp:function
|
immune checkpoint regulation
inhibition of T-cell activation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
17635
|
|
gptkbp:interactsWith
|
PD-1 receptor
|
|
gptkbp:locatedOnChromosome
|
gptkb:9p24.1
gptkb:chromosome_9
|
|
gptkbp:mutationAssociatedWith
|
immune evasion
tumor progression
|
|
gptkbp:OMIM
|
605402
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:product
|
PD-L1 protein
|
|
gptkbp:regulates
|
gptkb:immune_response
|
|
gptkbp:target
|
gptkb:immunotherapy
checkpoint inhibitors
|
|
gptkbp:UniProtID
|
Q9NZQ7
|
|
gptkbp:bfsParent
|
gptkb:programmed_death-ligand_1
gptkb:programmed_death-ligand_1_(PD-L1)
gptkb:CD274
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD274 gene
|