Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:CD274
PD-L1 |
| gptkbp:binds |
gptkb:PD-1
|
| gptkbp:discoveredIn |
1999
|
| gptkbp:encodedBy |
gptkb:CD274_gene
|
| gptkbp:expressedIn |
tumor cells
antigen-presenting cells |
| gptkbp:foundIn |
humans
|
| gptkbp:function |
immune checkpoint protein
|
| https://www.w3.org/2000/01/rdf-schema#label |
B7-H1
|
| gptkbp:inhibitedBy |
immune response
|
| gptkbp:involves |
autoimmune diseases
cancer immune evasion |
| gptkbp:locatedOnChromosome |
chromosome 9p24.1
|
| gptkbp:memberOf |
gptkb:B7_family
|
| gptkbp:molecularWeight |
33 kDa
|
| gptkbp:regulates |
T cell activation
|
| gptkbp:structureType |
type I transmembrane protein
|
| gptkbp:target |
immunotherapy
checkpoint inhibitors |
| gptkbp:bfsParent |
gptkb:programmed_death-ligand_1_(PD-L1)
|
| gptkbp:bfsLayer |
7
|