MASP-1

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy gptkb:MASP-2
gptkb:complement_component_C2
gptkb:complement_component_C4
gptkbp:alternativeName MBL-associated serine protease 1
gptkbp:associatedWith 3MC syndrome
gptkbp:discoveredBy 1998
gptkbp:encodedBy MASP1 gene
gptkbp:enzymeCommissionNumber EC 3.4.21.104
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:fullName Mannan-binding lectin serine protease 1
gptkbp:function gptkb:serine_protease
complement system activation
gptkbp:gene MASP1
https://www.w3.org/2000/01/rdf-schema#label MASP-1
gptkbp:interactsWith MBL (mannan-binding lectin)
ficolin
gptkbp:locatedOnChromosome chromosome 3q27-q28
gptkbp:OMIM 605791
gptkbp:pathway lectin pathway of complement activation
gptkbp:relatedTo innate immunity
gptkbp:structure contains serine protease domain
gptkbp:UniProtID Q13114
gptkbp:bfsParent gptkb:Mannose-binding_lectin
gptkbp:bfsLayer 7