Statements (25)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:activatedBy |
gptkb:MASP-2
gptkb:complement_component_C2 gptkb:complement_component_C4 |
gptkbp:alternativeName |
MBL-associated serine protease 1
|
gptkbp:associatedWith |
3MC syndrome
|
gptkbp:discoveredBy |
1998
|
gptkbp:encodedBy |
MASP1 gene
|
gptkbp:enzymeCommissionNumber |
EC 3.4.21.104
|
gptkbp:foundIn |
gptkb:Homo_sapiens
|
gptkbp:fullName |
Mannan-binding lectin serine protease 1
|
gptkbp:function |
gptkb:serine_protease
complement system activation |
gptkbp:gene |
MASP1
|
https://www.w3.org/2000/01/rdf-schema#label |
MASP-1
|
gptkbp:interactsWith |
MBL (mannan-binding lectin)
ficolin |
gptkbp:locatedOnChromosome |
chromosome 3q27-q28
|
gptkbp:OMIM |
605791
|
gptkbp:pathway |
lectin pathway of complement activation
|
gptkbp:relatedTo |
innate immunity
|
gptkbp:structure |
contains serine protease domain
|
gptkbp:UniProtID |
Q13114
|
gptkbp:bfsParent |
gptkb:Mannose-binding_lectin
|
gptkbp:bfsLayer |
7
|