Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
C4
C2 |
| gptkbp:associatedWith |
MASP2 deficiency
increased susceptibility to infection |
| gptkbp:discoveredBy |
1998
|
| gptkbp:EC_number |
3.4.21.104
|
| gptkbp:encodedBy |
MASP2 gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:fullName |
Mannan-binding lectin serine protease 2
|
| gptkbp:function |
gptkb:serine_protease
complement activation |
| gptkbp:gene |
MASP2
|
| https://www.w3.org/2000/01/rdf-schema#label |
MASP-2
|
| gptkbp:locatedOnChromosome |
gptkb:1p36.23
|
| gptkbp:molecularWeight |
74 kDa
|
| gptkbp:OMIM |
605102
|
| gptkbp:pathway |
lectin pathway of complement system
|
| gptkbp:relatedTo |
innate immunity
|
| gptkbp:structure |
contains CUB, EGF, CCP, and serine protease domains
|
| gptkbp:UniProtID |
O00187
|
| gptkbp:bfsParent |
gptkb:Mannose-binding_lectin
|
| gptkbp:bfsLayer |
7
|