C-X-C chemokine receptor type 7

URI: https://gptkb.org/entity/C-X-C_chemokine_receptor_type_7
GPTKB entity
Statements (46)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:G_protein-coupled_receptor
gptkbp:alternativeName gptkb:CXCR7
gptkb:ACKR3
RDC1
gptkbp:associatedWith gptkb:cancer
gptkb:cardiovascular_disease
inflammatory bowel disease
gptkbp:binds gptkb:CXCL11
gptkb:CXCL12
gptkbp:biologicalProcess signal transduction
chemokine binding
gptkbp:encodedBy gptkb:ACKR3_gene
gptkbp:Entrez_Gene_ID 57007
ENSG00000196628
gptkbp:expressedIn gptkb:cancer
gptkb:kidney
gptkb:placenta
brain
heart
liver
spleen
lymph node
endothelial cells
gptkbp:function chemokine receptor activity
gptkbp:HGNC_ID 1816
https://www.w3.org/2000/01/rdf-schema#label C-X-C chemokine receptor type 7
gptkbp:locatedIn gptkb:cell_membrane
gptkbp:locatedOnChromosome 2q37.1
gptkbp:OMIM 610425
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologIn gptkb:Mus_musculus
gptkb:Rattus_norvegicus
gptkbp:RefSeq NM_020311
gptkbp:regulates cell proliferation
cell survival
cell adhesion
CXCL12 availability
gptkbp:role angiogenesis
cell migration
immune response
tumor progression
gptkbp:UniProtID P25106
gptkbp:bfsParent gptkb:CXCR7
gptkb:ACKR3
gptkbp:bfsLayer 8