|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:ATCCode
|
gptkb:C07
|
|
gptkbp:canBe
|
gptkb:Anxiety
gptkb:Thyrotoxicosis
glaucoma
Migraine prophylaxis
|
|
gptkbp:canWorsen
|
gptkb:Peripheral_vascular_disease
gptkb:Raynaud's_phenomenon
gptkb:Chronic_obstructive_pulmonary_disease
|
|
gptkbp:category
|
Antiarrhythmic agent
Antihypertensive agent
Cardiovascular drug
|
|
gptkbp:cause
|
Depression
Sexual dysfunction
Masking of hypoglycemia symptoms
|
|
gptkbp:contraindication
|
Asthma
Heart block
Severe bradycardia
|
|
gptkbp:criteria
|
Beta-1 selective
Non-selective
|
|
gptkbp:discoveredIn
|
1960s
|
|
gptkbp:eliminatedIn
|
Hepatic
Renal
|
|
gptkbp:example
|
gptkb:Bisoprolol
gptkb:Carvedilol
gptkb:Esmolol
gptkb:Metoprolol
gptkb:Nebivolol
gptkb:Atenolol
gptkb:Propranolol
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Beta Blockers
|
|
gptkbp:interactsWith
|
gptkb:Clonidine
gptkb:Insulin
Calcium channel blockers
|
|
gptkbp:inventedBy
|
gptkb:James_Black
|
|
gptkbp:mechanismOfAction
|
Block beta-adrenergic receptors
|
|
gptkbp:pregnancyCategory
|
C (varies by agent)
|
|
gptkbp:routeOfAdministration
|
gptkb:Oral
Intravenous
|
|
gptkbp:sideEffect
|
gptkb:Bradycardia
Dizziness
Fatigue
Cold extremities
|
|
gptkbp:target
|
gptkb:Beta-1_adrenergic_receptor
Beta-2 adrenergic receptor
|
|
gptkbp:usedFor
|
Heart failure
Arrhythmia
Hypertension
Myocardial infarction
Angina
|
|
gptkbp:bfsParent
|
gptkb:Anti-Anxiety_Agents
|
|
gptkbp:bfsLayer
|
7
|