|
gptkbp:instanceOf
|
hormone
|
|
gptkbp:administeredBy
|
gptkb:Humans
gptkb:Injection
Animals
Insulin pump
|
|
gptkbp:approvedForMedicalUse
|
Yes
|
|
gptkbp:CASNumber
|
9004-10-8
|
|
gptkbp:category
|
gptkb:protein
Endocrinology
Essential medicine
Peptide hormone
Antidiabetic medication
|
|
gptkbp:contraindication
|
Hypersensitivity
|
|
gptkbp:deficiencyCauses
|
gptkb:Type_1_diabetes
|
|
gptkbp:discoveredBy
|
gptkb:Frederick_Banting
gptkb:Charles_Best
gptkb:James_Collip
gptkb:John_Macleod
|
|
gptkbp:discoveredIn
|
1921
|
|
gptkbp:essentialMedicine
|
gptkb:WHO_Model_List_of_Essential_Medicines
|
|
gptkbp:firstUsedInHumans
|
1922
|
|
gptkbp:Gene
|
gptkb:INS
|
|
gptkbp:halfLife
|
4-6 minutes
|
|
gptkbp:hasMolecularFormula
|
C257H383N65O77S6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Insulin
|
|
gptkbp:inhibitedBy
|
gptkb:Gluconeogenesis
Lipolysis
|
|
gptkbp:marketedAs
|
gptkb:Actrapid
gptkb:Admelog
gptkb:Afrezza
gptkb:Apidra
gptkb:Basaglar
gptkb:Fiasp
gptkb:Humulin
gptkb:Hypurin
gptkb:Iletin
gptkb:Insulatard
gptkb:Insulin_aspart
gptkb:Insulin_degludec
gptkb:Insulin_detemir
gptkb:Insulin_glargine
gptkb:Insulin_glulisine
gptkb:Insulin_lispro
gptkb:Insuman
gptkb:Levemir
gptkb:Mixtard
gptkb:Novolin
gptkb:Protaphane
gptkb:Ryzodeg
gptkb:Soliqua
gptkb:Tresiba
gptkb:Velosulin
gptkb:Xultophy
gptkb:NPH_insulin
gptkb:Lente
gptkb:Ultralente
gptkb:NovoRapid
gptkb:Humalog
gptkb:Lantus
gptkb:Toujeo
Bovine insulin
Insulin human
Porcine insulin
Biosynthetic insulin
Inhaled insulin
Insulin analog
Oral insulin (experimental)
Recombinant insulin
Regular insulin
Semilente
|
|
gptkbp:MeSH_ID
|
D007328
|
|
gptkbp:NobelPrizeYear
|
1923 Nobel Prize in Physiology or Medicine
|
|
gptkbp:producedBy
|
Pancreas
Beta cells
|
|
gptkbp:product
|
Peptide hormone
|
|
gptkbp:promotion
|
gptkb:Glycogenesis
Fat storage
Protein synthesis
|
|
gptkbp:PubChem_CID
|
16132288
|
|
gptkbp:recipient
|
gptkb:Insulin_receptor
|
|
gptkbp:regulates
|
Blood glucose
|
|
gptkbp:requires
|
Glucose uptake
|
|
gptkbp:resistanceCauses
|
gptkb:Type_2_diabetes
|
|
gptkbp:sideEffect
|
Weight gain
Hypoglycemia
Allergic reaction
Injection site reaction
|
|
gptkbp:storage
|
Refrigeration recommended
|
|
gptkbp:structure
|
A chain and B chain linked by disulfide bonds
|
|
gptkbp:UNII
|
IY9XDZ35W2
|
|
gptkbp:usedFor
|
gptkb:Diabetes_mellitus
|
|
gptkbp:bfsParent
|
gptkb:Glucagon
|
|
gptkbp:bfsLayer
|
6
|