Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
non-selective beta blocker alpha-1 blocker |
| gptkbp:approvalYear |
1993
1995 (US) |
| gptkbp:approvedBy |
gptkb:Germany
|
| gptkbp:ATCCode |
C07AG02
|
| gptkbp:bioavailability |
25%
|
| gptkbp:brand |
Coreg
Dilatrend Eucardic Kredex |
| gptkbp:CASNumber |
72956-09-3
|
| gptkbp:category |
beta blocker
antihypertensive agent alpha blocker |
| gptkbp:chemicalFormula |
C24H26N2O4
|
| gptkbp:contraindication |
asthma
severe liver impairment second or third degree AV block |
| gptkbp:discoveredBy |
gptkb:Boehringer_Mannheim
|
| gptkbp:eliminationHalfLife |
7-10 hours
|
| gptkbp:excretion |
urine
feces |
| https://www.w3.org/2000/01/rdf-schema#label |
Carvedilol
|
| gptkbp:KEGGID |
D00245
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
blocks alpha-1 adrenergic receptors
blocks beta-adrenergic receptors |
| gptkbp:MedlinePlusID |
a697042
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
406.48 g/mol
|
| gptkbp:pregnancyCategory |
C (US)
B3 (Australia) |
| gptkbp:proteinBinding |
98%
|
| gptkbp:PubChem_CID |
2585
CHEMBL229 DB01136 |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
dizziness
fatigue weight gain hypotension bradycardia |
| gptkbp:synonym |
BM 14190
Carvedilolum |
| gptkbp:UNII |
0K47UL67F2
|
| gptkbp:usedFor |
heart failure
hypertension left ventricular dysfunction after myocardial infarction |
| gptkbp:bfsParent |
gptkb:Beta_Blockers
|
| gptkbp:bfsLayer |
8
|