Statements (30)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
beta blocker |
gptkbp:approvalYear |
1986
|
gptkbp:ATCCode |
C07AB09
|
gptkbp:brand |
Brevibloc
|
gptkbp:CASNumber |
81147-92-4
|
gptkbp:chemicalFormula |
C16H25NO4
|
gptkbp:contraindication |
heart block
severe bradycardia cardiogenic shock |
gptkbp:discoveredBy |
gptkb:David_T._Wong
|
gptkbp:eliminationHalfLife |
9 minutes
|
https://www.w3.org/2000/01/rdf-schema#label |
Esmolol
|
gptkbp:legalStatus |
prescription only
|
gptkbp:mechanismOfAction |
beta-1 adrenergic receptor antagonist
|
gptkbp:metabolism |
plasma esterases
|
gptkbp:molecularWeight |
295.37 g/mol
|
gptkbp:pregnancyCategory |
C (US)
|
gptkbp:proteinBinding |
55%
|
gptkbp:routeOfAdministration |
intravenous
|
gptkbp:sideEffect |
nausea
fatigue hypotension bradycardia |
gptkbp:usedFor |
gptkb:atrial_fibrillation
gptkb:supraventricular_tachycardia hypertension atrial flutter |
gptkbp:bfsParent |
gptkb:Beta_Blockers
|
gptkbp:bfsLayer |
8
|