Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
beta blocker |
| gptkbp:approvedBy |
1978
|
| gptkbp:ATCCode |
C07AB02
|
| gptkbp:brand |
Lopressor
Toprol-XL |
| gptkbp:CASNumber |
37350-58-6
|
| gptkbp:contraindication |
asthma
severe bradycardia cardiogenic shock |
| gptkbp:discoveredBy |
gptkb:AstraZeneca
|
| gptkbp:eliminationHalfLife |
3-7 hours
|
| gptkbp:excretion |
urine
|
| gptkbp:hasMolecularFormula |
C15H25NO3
|
| https://www.w3.org/2000/01/rdf-schema#label |
Metoprolol
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
beta-1 adrenergic receptor antagonist
|
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:proteinBinding |
12%
|
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:sideEffect |
gptkb:depression
dizziness fatigue hypotension bradycardia |
| gptkbp:usedFor |
gptkb:arrhythmia
heart failure myocardial infarction hypertension angina |
| gptkbp:bfsParent |
gptkb:Zentiva
|
| gptkbp:bfsLayer |
7
|