Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
alpha-2 adrenergic agonist antihypertensive agent |
| gptkbp:ATCCode |
C02AC01
|
| gptkbp:availableOn |
gptkb:tablet
musical composition injection |
| gptkbp:brand |
Catapres
Kapvay Dixarit |
| gptkbp:CASNumber |
4205-90-7
|
| gptkbp:chemicalClass |
imidazoline derivative
|
| gptkbp:contraindication |
hypersensitivity to clonidine
|
| gptkbp:discoveredBy |
gptkb:Boehringer_Ingelheim
|
| gptkbp:eliminationHalfLife |
12-16 hours
|
| gptkbp:excretion |
gptkb:kidney
|
| gptkbp:hasMolecularFormula |
C9H9Cl2N3
|
| https://www.w3.org/2000/01/rdf-schema#label |
Clonidine
|
| gptkbp:introducedIn |
1966
|
| gptkbp:KEGGID |
D07718
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
stimulates alpha-2 adrenergic receptors
|
| gptkbp:MedlinePlusID |
a682243
|
| gptkbp:meltingPoint |
153-154°C
|
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:PubChem_CID |
2803
2699 DB00575 CHEMBL59 |
| gptkbp:routeOfAdministration |
oral
transdermal epidural |
| gptkbp:sideEffect |
constipation
dizziness fatigue drowsiness hypotension dry mouth bradycardia |
| gptkbp:synonym |
2-(2,6-dichlorophenylamino)-2-imidazoline
|
| gptkbp:UNII |
MN3L5RMN02
|
| gptkbp:usedFor |
ADHD
pain management hypertension Tourette syndrome anxiety disorders opioid withdrawal menopausal hot flashes |
| gptkbp:WHOModelListOfEssentialMedicines |
yes
|
| gptkbp:bfsParent |
gptkb:Beta_Blockers
|
| gptkbp:bfsLayer |
8
|