Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:component |
TGF-beta receptor superfamily
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:example |
gptkb:BMPR1A
gptkb:BMPR1B gptkb:BMPR2 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
bind bone morphogenetic proteins
transduce BMP signaling |
| https://www.w3.org/2000/01/rdf-schema#label |
BMP receptors
|
| gptkbp:ligand |
gptkb:BMP2
gptkb:BMP4 gptkb:BMP7 |
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:mutationAssociatedWith |
pulmonary arterial hypertension
skeletal disorders |
| gptkbp:role |
cell differentiation
embryonic development bone formation organogenesis |
| gptkbp:subspecies |
type I BMP receptor
type II BMP receptor |
| gptkbp:type |
serine/threonine kinase receptor
|
| gptkbp:bfsParent |
gptkb:BMP_signaling_pathway
gptkb:SMAD gptkb:bone_morphogenetic_protein-2_(BMP-2) |
| gptkbp:bfsLayer |
7
|