RhoGEF domain

GPTKB entity

Statements (18)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:Dbl_homology_domain
gptkbp:associatedWith cell signaling
cytoskeletal organization
gptkbp:discoveredIn Dbl oncogene protein
gptkbp:enables GDP-GTP exchange
gptkbp:foundIn Rho guanine nucleotide exchange factors
gptkbp:function activates Rho GTPases
https://www.w3.org/2000/01/rdf-schema#label RhoGEF domain
gptkbp:interactsWith Rho family GTPases
gptkbp:InterPro IPR000219
gptkbp:oftenFoundWith Pleckstrin homology domain
gptkbp:presentIn many eukaryotic proteins
gptkbp:proteinFamily PF00621
PS50021
gptkbp:structure mainly alpha-helical
gptkbp:bfsParent gptkb:BCR
gptkbp:bfsLayer 7