|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activity
|
GTPase activity
|
|
gptkbp:alias
|
ADP-ribosylation factor 6
ARF-6
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
|
|
gptkbp:Entrez_Gene_ID
|
382
|
|
gptkbp:family
|
gptkb:ARF_family
|
|
gptkbp:fullName
|
ADP-ribosylation factor 6
|
|
gptkbp:function
|
regulation of membrane trafficking
actin cytoskeleton remodeling
|
|
gptkbp:gene
|
gptkb:ARF6
|
|
gptkbp:GO
|
GO:0007264 (small GTPase mediated signal transduction)
GO:0006897 (endocytosis)
GO:0007010 (cytoskeleton organization)
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ARF6
|
|
gptkbp:interactsWith
|
gptkb:EFA6
gptkb:Rac1
gptkb:Rab11
PLD1
CYTH2
GGA3
|
|
gptkbp:locatedOnChromosome
|
14q21-q22
|
|
gptkbp:location
|
gptkb:plasma_membrane
endosomes
|
|
gptkbp:molecularWeight
|
20 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
1E0S
|
|
gptkbp:postTranslationalModification
|
phosphorylation
myristoylation
|
|
gptkbp:regulates
|
gptkb:GAPs_(GTPase-activating_proteins)
gptkb:GEFs_(guanine_nucleotide_exchange_factors)
cell migration
cytoskeletal organization
endocytosis
exocytosis
|
|
gptkbp:structure
|
gptkb:GTP-binding_domain
|
|
gptkbp:subfamily
|
small molecule
|
|
gptkbp:UniProtID
|
P62330
|
|
gptkbp:bfsParent
|
gptkb:Arf_family
gptkb:Arf_protein
|
|
gptkbp:bfsLayer
|
6
|