|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
no
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:Coronary_artery_disease
gptkb:cardiovascular_disease
gptkb:dementia
gptkb:Type_III_hyperlipoproteinemia
Stroke
Atherosclerosis
|
|
gptkbp:biologicalProcess
|
cholesterol homeostasis
lipid binding
lipoprotein metabolic process
receptor binding
|
|
gptkbp:discoveredBy
|
gptkb:Allen_D._Roses
|
|
gptkbp:encodes
|
apolipoprotein E protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000130203
348
|
|
gptkbp:expressedIn
|
brain
liver
macrophages
|
|
gptkbp:fullName
|
gptkb:Apolipoprotein_E
|
|
gptkbp:function
|
cholesterol metabolism
lipid transport
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
gptkb:GO:0005509
gptkb:GO:0006869
gptkb:GO:0008033
gptkb:GO:0008203
gptkb:GO:0008289
gptkb:GO:0034369
gptkb:GO:0034379
|
|
gptkbp:hasAllele
|
gptkb:APOE_ε2
gptkb:APOE_ε3
gptkb:APOE_ε4
|
|
gptkbp:hasPolymorphism
|
gptkb:rs429358
gptkb:rs7412
|
|
gptkbp:HGNC_ID
|
HGNC:613
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
APOE
|
|
gptkbp:length
|
359 amino acids
|
|
gptkbp:locatedOnChromosome
|
19
19q13.32
|
|
gptkbp:locusType
|
19q13.32
|
|
gptkbp:OMIM
|
107741
|
|
gptkbp:orthologInMouse
|
gptkb:Apoe
|
|
gptkbp:proteinFamily
|
apolipoprotein family
|
|
gptkbp:symbol
|
gptkb:APOE
|
|
gptkbp:UniProtID
|
P02649
|
|
gptkbp:bfsParent
|
gptkb:APOE-e2
gptkb:APOE_gene
gptkb:chromosome_19
gptkb:apolipoprotein_E
|
|
gptkbp:bfsLayer
|
6
|