|
gptkbp:instanceOf
|
ionotropic glutamate receptor
|
|
gptkbp:composedOf
|
gptkb:GluA1_subunit
gptkb:GluA2_subunit
gptkb:GluA3_subunit
gptkb:GluA4_subunit
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:encodedBy
|
gptkb:GRIA1_gene
gptkb:GRIA2_gene
gptkb:GRIA3_gene
gptkb:GRIA4_gene
|
|
gptkbp:enemyOf
|
gptkb:AMPA
gptkb:CNQX
gptkb:NBQX
|
|
gptkbp:expressedIn
|
neurons
glial cells
|
|
gptkbp:foundIn
|
central nervous system
|
|
gptkbp:function
|
mediate fast synaptic transmission
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AMPA receptors
|
|
gptkbp:involvedIn
|
gptkb:synaptic_plasticity
gptkb:long-term_potentiation
memory
learning
|
|
gptkbp:ligand
|
glutamate
|
|
gptkbp:modulatedBy
|
gptkb:TARP_proteins
|
|
gptkbp:namedAfter
|
gptkb:AMPA_(α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic_acid)
|
|
gptkbp:permeableTo
|
potassium ions
sodium ions
|
|
gptkbp:relatedTo
|
gptkb:NMDA_receptors
gptkb:kainate_receptors
|
|
gptkbp:sometimesPermeableTo
|
calcium ions
|
|
gptkbp:synonym
|
gptkb:AMPA-type_glutamate_receptor
gptkb:GluA_receptor
|
|
gptkbp:type
|
tetrameric protein complex
|
|
gptkbp:bfsParent
|
gptkb:place_cells
gptkb:Daniel_Choquet
|
|
gptkbp:bfsLayer
|
7
|