GRIA1 gene

GPTKB entity

Statements (36)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias gptkb:GluA1
GLUR1
GluR-A
HBGR1
gptkbp:alternativeSplicing yes
gptkbp:associatedWith synaptic transmission
learning and memory
excitatory neurotransmission
gptkbp:discoveredIn 1990s
gptkbp:encodes GluA1 protein
gptkbp:Entrez_Gene_ID 2890
ENSG00000155511
gptkbp:expressedIn gptkb:cerebral_cortex
brain
hippocampus
gptkbp:fullName glutamate ionotropic receptor AMPA type subunit 1
gptkbp:function codes for a subunit of the AMPA receptor
gptkbp:HGNC_ID HGNC:4573
https://www.w3.org/2000/01/rdf-schema#label GRIA1 gene
gptkbp:locatedOnChromosome 5q33.2
gptkbp:mutationAssociatedWith intellectual disability
neurodevelopmental disorders
gptkbp:OMIM 138248
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Gria1
gptkbp:product AMPA receptor subunit GluA1
gptkbp:recipient ionotropic glutamate receptor
gptkbp:relatedTo gptkb:synaptic_plasticity
gptkb:long-term_potentiation
excitatory postsynaptic potential
gptkbp:subunit gptkb:AMPA_receptor
gptkbp:UniProtID P42261
gptkbp:bfsParent gptkb:AMPA_receptors
gptkb:GluA1
gptkbp:bfsLayer 8