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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alsoKnownAs
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gptkb:GRIA1
glutamate receptor 1
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gptkbp:component
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gptkb:AMPA_receptor
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gptkbp:discoveredIn
|
1990s
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gptkbp:encodedBy
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gptkb:GRIA1_gene
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gptkbp:form
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heteromeric channels
homomeric channels
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gptkbp:foundIn
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central nervous system
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gptkbp:function
|
involved in synaptic plasticity
mediates fast synaptic transmission
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|
https://www.w3.org/2000/01/rdf-schema#label
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GluA1 subunit
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gptkbp:interactsWith
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gptkb:GluA2_subunit
gptkb:GluA3_subunit
gptkb:GluA4_subunit
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gptkbp:involvedIn
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gptkb:long-term_potentiation
learning and memory
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gptkbp:ligand
|
glutamate
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gptkbp:locale
|
postsynaptic membrane
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gptkbp:locatedOnChromosome
|
5q33.2
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gptkbp:modulatedBy
|
phosphorylation
RNA editing
alternative splicing
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gptkbp:molecularWeight
|
~100 kDa
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gptkbp:relatedTo
|
neuropsychiatric disorders
excitatory neurotransmission
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gptkbp:species
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gptkb:Mus_musculus
gptkb:Homo_sapiens
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gptkbp:structure
|
transmembrane protein
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gptkbp:UniProtID
|
P42261
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gptkbp:bfsParent
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gptkb:AMPA_receptors
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gptkbp:bfsLayer
|
8
|