Statements (40)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
ionotropic glutamate receptor |
| gptkbp:activatedBy |
gptkb:kainic_acid
glutamate |
| gptkbp:alternativeName |
GLUK receptors
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodedBy |
GRIK genes
|
| gptkbp:enemyOf |
gptkb:CNQX
gptkb:NBQX gptkb:UBP302 gptkb:kainic_acid domoic acid |
| gptkbp:foundIn |
central nervous system
|
| gptkbp:function |
mediate excitatory neurotransmission
|
| gptkbp:gene |
gptkb:GRIK1
gptkb:GRIK2 gptkb:GRIK3 gptkb:GRIK4 gptkb:GRIK5 |
| https://www.w3.org/2000/01/rdf-schema#label |
kainate receptors
|
| gptkbp:location |
postsynaptic membrane
presynaptic membrane |
| gptkbp:modulatedBy |
gptkb:ATP
zinc |
| gptkbp:permeableTo |
potassium ions
sodium ions |
| gptkbp:relatedTo |
gptkb:AMPA_receptors
gptkb:NMDA_receptors |
| gptkbp:role |
gptkb:synaptic_plasticity
epilepsy neurotoxicity |
| gptkbp:structure |
tetrameric
|
| gptkbp:subunit |
gptkb:GluK1
gptkb:GluK2 gptkb:GluK3 gptkb:GluK4 gptkb:GluK5 |
| gptkbp:bfsParent |
gptkb:AMPA_receptors
gptkb:kainic_acid |
| gptkbp:bfsLayer |
8
|