ALK protein

URI: https://gptkb.org/entity/ALK_protein

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:associatedWith	gptkb:anaplastic_large_cell_lymphoma gptkb:neuroblastoma gptkb:non-small_cell_lung_cancer
gptkbp:discoveredBy	gptkb:Steven_A._Morris
gptkbp:discoveredIn	1994
gptkbp:encodedBy	gptkb:ALK_gene
gptkbp:fullName	gptkb:anaplastic_lymphoma_kinase
gptkbp:function	gptkb:receptor_tyrosine_kinase cell growth regulation neuronal development
gptkbp:HGNC_ID	427
https://www.w3.org/2000/01/rdf-schema#label	ALK protein
gptkbp:locatedOnChromosome	2p23
gptkbp:location	gptkb:cell_membrane
gptkbp:molecularWeight	~220 kDa
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:structure	transmembrane protein
gptkbp:target	gptkb:alectinib gptkb:ceritinib gptkb:crizotinib gptkb:lorlatinib
gptkbp:UniProtID	gptkb:Q9UM73
gptkbp:bfsParent	gptkb:ALK_gene gptkb:anaplastic_large_cell_lymphoma_cells gptkb:systemic_ALK-positive_anaplastic_large_cell_lymphoma
gptkbp:bfsLayer	8