Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
gptkb:aggrecanase-2
|
| gptkbp:associatedWith |
osteoarthritis
|
| gptkbp:biologicalProcess |
peptidase activity
|
| gptkbp:Entrez_Gene_ID |
ENSG00000154734
11096 |
| gptkbp:expressedIn |
collagen
synovium |
| gptkbp:family |
gptkb:ADAMTS_family
|
| gptkbp:fullName |
gptkb:A_disintegrin_and_metalloproteinase_with_thrombospondin_motifs_5
|
| gptkbp:function |
degrades aggrecan in cartilage
metalloproteinase activity |
| gptkbp:geneType |
protein-coding
|
| gptkbp:GO_term |
GO:0004222
|
| gptkbp:HGNC_ID |
HGNC:222
|
| https://www.w3.org/2000/01/rdf-schema#label |
ADAMTS5
|
| gptkbp:inhibitedBy |
gptkb:TIMP3
|
| gptkbp:locatedOnChromosome |
21
21q21.3 |
| gptkbp:OMIM |
605011
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:substrate |
gptkb:aggrecan
gptkb:versican |
| gptkbp:UniProtID |
Q9UNA0
|
| gptkbp:bfsParent |
gptkb:chromosome_1q32
|
| gptkbp:bfsLayer |
7
|