|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:affiliatedWith
|
lectican family
|
|
gptkbp:alternativeSplicing
|
V0 isoform
V1 isoform
V2 isoform
V3 isoform
|
|
gptkbp:associatedWith
|
gptkb:cardiovascular_disease
cancer progression
inflammation
|
|
gptkbp:binds
|
gptkb:P-selectin
gptkb:integrins
gptkb:CD44
|
|
gptkbp:contains
|
chondroitin sulfate chains
|
|
gptkbp:discoveredBy
|
Ruhrberg et al.
|
|
gptkbp:encodedBy
|
VCAN gene
|
|
gptkbp:expressedIn
|
gptkb:skin
gptkb:nervous_system
heart
collagen
blood vessels
|
|
gptkbp:firstDescribed
|
1992
|
|
gptkbp:foundIn
|
extracellular matrix
|
|
gptkbp:function
|
cell proliferation
cell migration
cell adhesion
tissue morphogenesis
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
versican
|
|
gptkbp:interactsWith
|
gptkb:fibronectin
hyaluronan
tenascin-R
|
|
gptkbp:locatedOnChromosome
|
chromosome 5q14.2
|
|
gptkbp:molecularWeight
|
~1000 kDa
|
|
gptkbp:OMIM
|
118661
|
|
gptkbp:postTranslationalModification
|
glycosylation
proteolytic cleavage
|
|
gptkbp:role
|
embryonic development
wound healing
tumor microenvironment
|
|
gptkbp:UniProtID
|
P13611
|
|
gptkbp:bfsParent
|
gptkb:ADAMTS5
gptkb:Proteoglycans_in_cancer
gptkb:chondroitin_sulfate_proteoglycan
|
|
gptkbp:bfsLayer
|
8
|