3-phosphoinositide dependent protein kinase-1
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:activatedBy |
gptkb:phosphatidylinositol_(3,4,5)-trisphosphate
|
| gptkbp:alternativeName |
gptkb:PDPK1
gptkb:PDK1 |
| gptkbp:discoveredBy |
1997
|
| gptkbp:EC_number |
2.7.11.1
|
| gptkbp:encodedBy |
gptkb:PDPK1_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
regulates metabolism
regulates cell survival phosphorylates and activates AGC family kinases regulates cell growth |
| gptkbp:gene |
gptkb:PDPK1
|
| https://www.w3.org/2000/01/rdf-schema#label |
3-phosphoinositide dependent protein kinase-1
|
| gptkbp:involves |
gptkb:PI3K/AKT_signaling_pathway
|
| gptkbp:locatedIn |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:locatedOnChromosome |
16p13.3
|
| gptkbp:molecularWeight |
63 kDa
|
| gptkbp:phosphorylates |
gptkb:AKT1
gptkb:S6K gptkb:SGK gptkb:PKC |
| gptkbp:regulates |
apoptosis
cell proliferation protein synthesis glucose metabolism |
| gptkbp:structure |
contains PH domain
contains kinase domain |
| gptkbp:UniProtID |
gptkb:O15530
|
| gptkbp:bfsParent |
gptkb:PDPK1_gene
|
| gptkbp:bfsLayer |
7
|