Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:actsOn |
target protein
|
| gptkbp:alternativeName |
gptkb:E3_ubiquitin-protein_ligase
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:EC_number |
6.3.2.-
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
catalyzes transfer of ubiquitin
|
| https://www.w3.org/2000/01/rdf-schema#label |
ubiquitin ligase
|
| gptkbp:interactsWith |
gptkb:E1_ubiquitin-activating_enzyme
gptkb:E2_ubiquitin-conjugating_enzyme ubiquitin |
| gptkbp:involvedIn |
ubiquitination
|
| gptkbp:involves |
gptkb:cancer
neurodegenerative diseases immune response |
| gptkbp:regulates |
signal transduction
cell cycle protein degradation |
| gptkbp:requires |
gptkb:E2_ubiquitin-conjugating_enzyme
|
| gptkbp:subclassOf |
gptkb:HECT-type_ubiquitin_ligase
gptkb:RING-type_ubiquitin_ligase gptkb:U-box-type_ubiquitin_ligase |
| gptkbp:bfsParent |
gptkb:Anaphase-Promoting_Complex
gptkb:ligase gptkb:APC_complex |
| gptkbp:bfsLayer |
6
|