TCAs

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf abbreviation
gptkbp:contraindication severe liver disease
recent myocardial infarction
gptkbp:discoveredIn 1950s
gptkbp:drugClass antidepressant
gptkbp:example gptkb:doxepin
gptkb:amitriptyline
gptkb:imipramine
gptkb:clomipramine
gptkb:nortriptyline
https://www.w3.org/2000/01/rdf-schema#label TCAs
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction inhibit reuptake of norepinephrine and serotonin
gptkbp:overdoseSymptoms high
gptkbp:replacedBy gptkb:SSRIs
gptkbp:sideEffect gptkb:arrhythmia
gptkb:orthostatic_hypotension
constipation
weight gain
drowsiness
dry mouth
urinary retention
gptkbp:standsFor gptkb:tricyclic_antidepressants
gptkbp:usedFor treatment of chronic pain
treatment of depression
treatment of anxiety disorders
treatment of migraine prevention
gptkbp:bfsParent gptkb:Tranylcypromine
gptkb:phenelzine
gptkb:tranylcypromine
gptkbp:bfsLayer 7