Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:abbreviation
|
| gptkbp:contraindication |
severe liver disease
recent myocardial infarction |
| gptkbp:discoveredIn |
1950s
|
| gptkbp:drugClass |
gptkb:antidepressant
|
| gptkbp:example |
gptkb:doxepin
gptkb:amitriptyline gptkb:imipramine gptkb:clomipramine gptkb:nortriptyline |
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibit reuptake of norepinephrine and serotonin
|
| gptkbp:overdoseSymptoms |
high
|
| gptkbp:replacedBy |
gptkb:SSRIs
|
| gptkbp:sideEffect |
gptkb:arrhythmia
gptkb:orthostatic_hypotension constipation weight gain drowsiness dry mouth urinary retention |
| gptkbp:standsFor |
gptkb:tricyclic_antidepressants
|
| gptkbp:usedFor |
treatment of chronic pain
treatment of depression treatment of anxiety disorders treatment of migraine prevention |
| gptkbp:bfsParent |
gptkb:Tranylcypromine
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
TCAs
|