|
gptkbp:instanceOf
|
gptkb:transcription_factor
gptkb:protein
|
|
gptkbp:alias
|
gptkb:ERG1
gptkb:ETS-related_gene
p55
|
|
gptkbp:alternativeSplicing
|
multiple isoforms
|
|
gptkbp:associatedWith
|
gptkb:Ewing's_sarcoma
gptkb:acute_myeloid_leukemia
prostate cancer
|
|
gptkbp:binds
|
DNA sequence 5'-GGAA/T-3'
|
|
gptkbp:discoveredBy
|
Reddy et al.
|
|
gptkbp:domain
|
gptkb:ETS_domain
|
|
gptkbp:encodedBy
|
gptkb:ERG_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000157554
gptkb:ERG
|
|
gptkbp:expressedIn
|
hematopoietic cells
endothelial cells
|
|
gptkbp:firstDescribed
|
1987
|
|
gptkbp:formsFusionGeneWith
|
gptkb:TMPRSS2
|
|
gptkbp:function
|
transcriptional activation
regulation of gene expression
DNA binding
|
|
gptkbp:fusionGeneAssociatedWith
|
prostate cancer
|
|
gptkbp:HGNC_ID
|
gptkb:ERG
|
|
gptkbp:involvedIn
|
angiogenesis
hematopoiesis
endothelial cell differentiation
|
|
gptkbp:locatedOnChromosome
|
chromosome 21q22.3
|
|
gptkbp:memberOf
|
gptkb:ETS_transcription_factor_family
|
|
gptkbp:molecularWeight
|
~54 kDa
|
|
gptkbp:OMIM
|
165080
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:right
|
|
gptkbp:PDB
|
4IRI
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
|
|
gptkbp:regulates
|
gptkb:VEGF_gene
ICAM2 gene
TIE1 gene
endothelial cell-specific genes
|
|
gptkbp:reviewedBy
|
gptkb:GeneCards
gptkb:NCBI_Gene
gptkb:OMIM
gptkb:UniProt
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
P11308
|
|
gptkbp:bfsParent
|
gptkb:ERG
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
transcription factor ERG
|