Statements (36)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antineoplastic_agent
gptkb:drug |
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
L01XX17
|
| gptkbp:brand |
gptkb:Hycamtin
|
| gptkbp:CASNumber |
gptkb:123948-87-8
|
| gptkbp:developedBy |
gptkb:camptothecin
|
| gptkbp:discoveredBy |
gptkb:SmithKline_Beecham
|
| gptkbp:eliminationHalfLife |
2-3 hours
|
| gptkbp:excretion |
urine
|
| gptkbp:hasMolecularFormula |
C23H23N3O5
|
| gptkbp:KEGGID |
gptkb:D02370
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
topoisomerase I inhibitor
|
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
D (US)
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL428
gptkb:DB00350 60700 |
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:sideEffect |
gptkb:anemia
nausea vomiting diarrhea fatigue neutropenia thrombocytopenia |
| gptkbp:synonym |
gptkb:NSC_609699
gptkb:SKF_104864-A |
| gptkbp:UNII |
YGJ1F93G8W
|
| gptkbp:usedFor |
gptkb:cancer
gptkb:Small_Cell_Lung_Cancer |
| gptkbp:bfsParent |
gptkb:multidrug_resistance-associated_protein_1
|
| gptkbp:bfsLayer |
6
|
| http://www.w3.org/2000/01/rdf-schema#label |
topotecan
|